
Lab Sites
Center for Functional Neuroimaging TechnologiesCenter for Acupuncture Neuroimaging
Biomedical Informatics Research Network
Biography
Bruce Rosen, M.D., Ph.D., is Director of the Athinoula A. Martinos Center for Biomedical Imaging at Massachusetts General Hospital and Professor of Radiology at Harvard Medical School, as well as Professor of Health Sciences and Technology at Harvard-MIT. A pioneer in functional neuroimaging, Dr. Rosen has spent more than three decades developing and applying advanced MRI and related technologies to better understand how the brain works—and how it changes in disease.
His research has led to many of the imaging tools used today to study brain function, blood flow, and metabolism, enabling scientists and clinicians around the world to investigate conditions such as stroke, dementia, brain tumors, and neurological and psychiatric disorders. More recently, his work has focused on integrating MRI with other imaging methods—such as PET, MEG, and optical imaging—to create a more complete picture of brain activity and its underlying biology.
Dr. Rosen has led several large, multi-institutional research initiatives, including the NIH Human Connectome Project and the Center for Functional Neuroimaging Technologies. A Fellow of the National Academy of Medicine and recipient of major honors from organizations including the Radiological Society of North America and the International Society for Magnetic Resonance in Medicine, he continues to shape the field of brain imaging through both scientific innovation and mentorship.
Recent Publications
- Evaluating brain mechanisms of combined vagus nerve stimulation and mindfulness training for migraine: A randomized 2 × 2 factorial clinical trial protocol.
Contemp Clin Trials: Schuman-Olivier Z, Marin F, Kinder LD, Datko M, Round K, Tohyama S, Garcia RG, Hirschtick RL, Edwards RR, Wells RE, Cheng HT, Barbieri R, Hadjikhani N, Loggia ML, Kaptchuk TJ, Houle TT, Rosen BR, Napadow V. - Quantifying axonal features of human superficial white matter from three-dimensional multibeam serial electron microscopy data assisted by deep learning.
Neuroimage: Tian Q, Ngamsombat C, Lee HH, Berger DR, Wu Y, Fan Q, Bilgic B, Li Z, Novikov DS, Fieremans E, Rosen BR, Lichtman JW, Huang SY. - Quantifying brain-wide cerebrospinal fluid flow dynamics using slow-flow-sensitized phase-contrast MRI.
bioRxiv: Dong Z, Wang F, Strom AK, Eckstein K, Bachrata B, Robinson SD, Rosen BR, Wald LL, Lewis LD, Polimeni JR. - Trigeminal nerve microstructure is linked with neuroinflammation and brainstem activity in migraine.
Brain: Tohyama S, Datko M, Brusaferri L, Kinder LD, Schnieders JH, Hyman M, Goldstein AM, Gilbert MD, Housman H, Le V, Round K, Marin F, Heffernan MR, Garcia RG, Gollub RL, Edwards RR, Rosen BR, Hadjikhani N, Cheng HT, Schuman-Olivier Z, Loggia ML, Napadow V. - Simultaneous EEG-PET-MRI identifies temporally coupled, spatially structured hemodynamic and metabolic dynamics across wakefulness and NREM sleep.
bioRxiv: Chen JE, Lewis LD, Coursey SE, Catana C, Polimeni JR, Fan J, Droppa KS, Patel R, Wey HY, Chang C, Manoach DS, Price JC, Sander CY, Rosen BR.