MRI scans taken before prostate cancer treatment may already contain clues about which patients are most at risk for the disease returning after radiation. In a new study, Onofrio A Catalano and colleagues analyzed pretreatment prostate MRIs and found that certain features — especially when the tumor appeared to press on or invade nearby nerves — were linked to a later rise in PSA levels, a common sign of recurrence. If validated in larger studies, these imaging clues could help doctors tailor follow-up care and catch potential relapses sooner.
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Herold A, Pohl M, Korn SM, Weber M, Efstathiou JA, Saylor PJ, Huang SY, Harisinghani MG, Catalano OA. Prognostic value of MRI-derived features for biochemical recurrence after curative radiotherapy in prostate cancer. Abdom Radiol (NY). 2025 Sep 20. doi: 10.1007/s00261-025-05199-x. Epub ahead of print. PMID: 40974477. (PubMed page)
Author: Gary Boas
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